Travel 21 miles north on U.S. Highway 425 from Star City to Pine Bluff, Arkansas. This rural route winds past farmland, small towns, and Grider Field before reaching the southern edge of Pine Bluff.

Explore U.S. Route 425, a north–south highway running from Natchez, Mississippi to Pine Bluff, Arkansas. Learn about its history, major intersections, and importance to local communities in Mississippi, Louisiana, and Arkansas.
U.S. Route 425 (US 425) is a north–south U.S. Highway that traverses the southern United States, spanning the states of Mississippi, Louisiana, and Arkansas. It runs approximately 220 miles from its southern terminus at Natchez, Mississippi, where it intersects with US 61 and US 84, to its northern end near Pine Bluff, Arkansas, at an intersection with US 65. Although not one of the oldest highways in the U.S. system, US 425 has grown in regional importance as a connector through rural communities and agricultural corridors.
The route winds through the heart of the Mississippi Delta and Deltaic Plain, offering access to smaller towns such as Winnsboro and Bastrop in Louisiana and Hamburg and Monticello in Arkansas. The highway often runs concurrent with other routes, such as LA 15 in Louisiana and US 82 near Crossett, Arkansas. While most of the roadway is two-lane, several segments—particularly near urban areas—have been upgraded to four-lane divided highways for improved traffic flow and safety.
US 425 is not a part of the original 1926 U.S. Highway system; it was commissioned later, with significant portions designated in the 1980s and 1990s. Today, it serves as a vital north–south alternative to more heavily trafficked corridors like US 65 and US 61, and it plays an essential role in local economies tied to agriculture, forestry, and manufacturing.

Travel 21 miles north on U.S. Highway 425 from Star City to Pine Bluff, Arkansas. This rural route winds past farmland, small towns, and Grider Field before reaching the southern edge of Pine Bluff.

Drive 22 miles north on US-425 from Monticello to Star City, Arkansas. This scenic Delta highway travels through farmland, forests, and small communities in Drew and Lincoln Counties.

Cruise 27 miles south along U.S. Highway 425 from Pine Bluff to Star City through the heart of southeast Arkansas farmland. Discover rural communities, local history, and a scenic stretch of highway connecting key small towns in the region.

Drive 12 miles along US Highway 425 from Ferriday, Louisiana, across the Mississippi River into historic Natchez, Mississippi. Explore scenic delta towns, riverfront views, and a key junction with US-84 on this short but memorable route.

Take a brief but meaningful drive along U.S. Route 425 through Natchez, Mississippi, as we follow this 2-mile segment from Canal Street to its southern end at US-61—linking downtown charm with a gateway to the Delta.

Drive 27 miles south on US-425 from the Arkansas border to Bastrop, Louisiana, through pine forests, farmland, and the scenic Chemin-A-Haut State Park. A peaceful ride through northeastern Louisiana’s bayou country.

Take a scenic drive along US-425 from US-82 to the Louisiana state line in southern Arkansas. Explore the pine forests, local history, and rural charm of this short but meaningful route through Ashley County.

Explore the scenic drive along US Highway 425 from Monticello to US-82 in southeastern Arkansas. This 36-mile route passes through rural towns, farmland, future interstate corridors, and historic communities, offering travelers a peaceful glimpse into Arkansas’ countrys…

Enjoy a scenic 22-mile drive along U.S. Route 425 from Star City to Monticello, Arkansas. Discover small-town charm, picturesque farmland, and welcoming rural communities.